DNA Damage and Repair
Nuclear myosin function in DNA damage
Myosins function in many nuclear processes. Along with transcription, we are investigating potential functions focused upon DNA damage detection and repair.
We are interested in how chromatin is altered during DNA damage and how this can lead to larger genomic rearrangements.
DNA damage signalling
We look at how DNA damage signalling impacts the localisation of myosin and actin to the nucleus.