DNA Damage and Repair

 
Figure1_Roleofnuclearmyosins.tiff

Nuclear myosin function in DNA damage

Myosins function in many nuclear processes. Along with transcription, we are investigating potential functions focused upon DNA damage detection and repair.

Chromosome Stain.tif

Genome Rearrangements

We are interested in how chromatin is altered during DNA damage and how this can lead to larger genomic rearrangements.

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DNA damage signalling

We look at how DNA damage signalling impacts the localisation of myosin and actin to the nucleus.